7-[5-Oxo-3-hydroxy-2-(3-substituted)-3-hydroxypropyl)-1- cyclope

Details 7-[5-Oxo-3-hydroxy-2-(3-substituted)-3-hydroxypropyl)-1- cyclope 7-[5-Oxo-3-hydroxy-2-(3-substituted)-3-hydroxypropyl)-1- cyclope

1981-04-16

1982-04-13

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 60, 560118, 562463, 562470, 562500, 424305, 424308, 424317, C07C17700

Patent

active

043249027

ABSTRACT:
7-[5-oxo-3-hydroxy-2-(3-substituted)-3-hydroxypropyl)-1-cyclopentene]-hepta noic acids having the following general formula ##STR1## wherein X is oxygen or hydroxyl, R.sub.1 and R.sub.3 are independently hydrogen or methyl, and R.sub.2 is --(CH.sub.2)n-Y where n is an integer from 0 through 4 inclusive, and Y is phenyl, or a cycloalkyl group having 4 to 6 carbon atoms. Said acids as well as certain derivatives thereof are useful as nasal decongestants, inhibitors of gastric secretion, inhibitors of platelet aggregation, blood additives, smooth muscle stimulators, hypotensive agents, labor inducers, and in controlling ovulation.

REFERENCES:
patent: 4076947 (1978-02-01), Schaub et al.

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