Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-12-04
1982-11-23
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544255, 544323, 544324, 548262, 548325, 548335, C07D49822, A61K 31505
Patent
active
043605214
ABSTRACT:
Oxadiazolo[2,3-c]pyrimidine derivatives of the formula ##STR1## wherein R is alkyl, alkenyl, alkynyl or alkoxyalkyl, as well as their salts, are described. The compounds of formula I have valuable, long-lasting vasodilating and/or blood pressure-lowering properties and are useful for the treatment of vascular-conditioned hypertensions or as vasodilators in peripheral blood supply disorders. The compounds are prepared, inter alia, by carbamoylating the corresponding derivative containing a free amino group and optional salt formation.
REFERENCES:
patent: 4150131 (1979-04-01), Muller et al.
patent: 4150132 (1979-04-01), Muller et al.
patent: 4220772 (1980-09-01), Muller et al.
patent: 4276417 (1981-06-01), Muller et al.
Hengartner Urs
Muller Jean-Claude
Ramuz Henri
Daus Donald G.
Gibson Sharon A.
Hoffmann-La Roche Inc.
Isgro William G.
Leon Bernard S.
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