6-piperidino-2,4-diaminopyrimidine-3-oxide salt of 3-carboxypyri

Details 6-piperidino-2,4-diaminopyrimidine-3-oxide salt of 3-carboxypyri 6-piperidino-2,4-diaminopyrimidine-3-oxide salt of 3-carboxypyri

1987-12-07

1989-09-12

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544298, A61K 31505

Patent

active

048660671

ABSTRACT:
The 6-piperidino-2,4-diaminopyrimidine-3-oxide salt of 3-carboxypyridine N-oxide, according to formula (I) ##STR1## is described. The compound (I) is useful in cosmetic and pharmaceutical field for the treatment of hair loss or of pathologic forms, such as alopecia, exfoliative dermatitis, etc. Topical formulations containing the compound (I) are also described.

REFERENCES:
patent: 3464987 (1969-09-01), Ursprung et al.
patent: 3637697 (1972-01-01), Anthony et al.
The New England Journal of Medicine (Dec. 18, 1980), vol. 303, No. 25, pp. 480-1481, "Reversal of Baldness in Patient Receiving Minoxidil for Hypertension", Anthony R. Zappacosta, MD.

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