6-Chloro-7,8- dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1

Details 6-Chloro-7,8- dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1 6-Chloro-7,8- dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1

1982-01-06

1983-06-14

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424244, A61K 3155, C07D22316

Patent

active

043882404

ABSTRACT:
New 6-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzaze pine hydrogen sulfate monoesters have been prepared and found to have potent renal dopaminergic activity. The most potent compound of the series is 6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-4'-yl-h ydrogen sulfate.

REFERENCES:
patent: 4197297 (1980-04-01), Weinstock

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