6-Aryl-4,5-dihydro-3(2H)-pyridazinones, and their use as anti-hy

Details 6-Aryl-4,5-dihydro-3(2H)-pyridazinones, and their use as anti-hy 6-Aryl-4,5-dihydro-3(2H)-pyridazinones, and their use as anti-hy

1983-03-11

1985-10-01

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544238, 544239, C07D23706, A61K 3150

Patent

active

045445621

ABSTRACT:
6-Aryl-4,5-dihydro-3(2H)-pyridazinones of the formula ##STR1## where R is hydrogen, R.sup.1 is hydrogen or C.sub.1 -C.sub.3 -alkyl, or R and R.sup.1 together are methylene, R.sup.2 and R.sup.3 are identical or different and are each hydrogen or C.sub.1 -C.sub.6 -alkyl, and A is hydroxyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.2 -C.sub.7 -acyloxy, a C.sub.2 -C.sub.7 -carbamic acid ester group, C.sub.1 -C.sub.6 -alkylsulfonyloxy, C.sub.1 -C.sub.6 -alkylmercapto, carboxyl, C.sub.2 -C.sub.7 -alkoxycarbonyl or nitrile, and their preparation are described. The substances are suitable for treating disorders.

REFERENCES:
patent: 3806509 (1974-04-01), Lebkuecher et al.
patent: 3824271 (1974-07-01), Allen, Jr. et al.
patent: 3888901 (1975-06-01), Allen, Jr. et al.

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