6-Acylamino-penam-3-carboxylic and 7-acylamino-3-cephem-4-carbox

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2602391, 260243C, 260251R, 2602564R, 2602565R, 424271, C07D50122, C07D50124, C07D50126

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active

040150003

ABSTRACT:
6-Acylamino-penam-3-carboxylic acids and 7-acylamino-3-cephem-4-carboxylic acids in which the acyl group has the formula ##STR1## IN WHICH R.sub.1 is hydrogen, R.sub.2 is optionally substituted phenyl, thienyl or furyl or R.sub.1 and R.sub.2 together are optionally substituted cycloalkyl, n and m independently of one another represent 0 or 1 and B represents an optionally substituted 2,6-dioxo- or 2,6-dithioxo-1,2,3,6-tetrahydro-pyrimidyl, 2-thioxo-6-oxo-1,2,3,6-tetrahydropyrimidyl, 2,6-dihydroxy- or 2,6-dimercapto-pyrimidyl, 2-mercapto-6-hydroxy-pyrimidyl, 2,6-diaminopyrimidyl, 2-amino-6-hydroxy-pyrimidyl or 2,6-dihalogenopyrimidyl radical, these radicals being bonded in the 4- or 5-position.

REFERENCES:
patent: 3322749 (1967-05-01), Crast
patent: 3499893 (1970-03-01), Crast
patent: 3825536 (1974-07-01), Berella et al.
patent: 3833570 (1974-09-01), Holdrege
patent: 3873523 (1975-03-01), Doub et al.
Schorr et al., "Chemical Abstracts," vol. 80, No. U-73, p. 300, abst. 37,130v.

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