5-[p-(Substituted)phenyl]-2,2-dialkyl-4-phenyl-3-oxazoline

Details 5-[p-(Substituted)phenyl]-2,2-dialkyl-4-phenyl-3-oxazoline 5-[p-(Substituted)phenyl]-2,2-dialkyl-4-phenyl-3-oxazoline

1981-11-12

1982-11-23

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548239, 260239A, 204158R, 564305, A61K 3142, C07D26310

Patent

active

043605303

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently, are hydrogen, halogen or lower alkyl; R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7, independently, are hydrogen or lower alkyl; R.sup.8 is hydrogen, lower alkyl or formyl; R.sup.9 and R.sup.10, independently, are methyl or trifluoromethyl; and n is 0 (zero) or, when both R.sup.7 and R.sup.8 are lower alkyl, n is 0 (zero) or 1, prepared, inter alia, from p-aminobenzaldehydes which may be N-alkyl substituted, are described. The compounds of formula I are orally active antidiabetic agents.

REFERENCES:
Giezendanner, H., et al., Helv. Chim. Acta., 56, 2611, (1973).
Giezendanner, H., et al., Helv. Chim. Acta., 55, 245, (1972).

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