5-membered ring compounds

Details 5-membered ring compounds 5-membered ring compounds

2001-02-06

2002-04-30

Padmanabhan, Sreeni (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

C568S064000, C568S338000, C568S379000, C562S503000

Reexamination Certificate

active

06380262

ABSTRACT:

This application is a 371 of PCT/JP99/04324 filed Aug. 10, 1999.
1. Technical Field
The present invention relates to a five-membered ring compound having physiological activities such as a carcinostatic activity which is useful in a field of medicine and a method for producing the compound.
2. Background Art
Wide variety of drugs including alkylating agents, antimetabolites, carcinostatics such as vegetable alkaloids, antibiotics, immunoenhancers and immnoregulators are conventionally used for clinical therapies. However, pharmacotherapy using such drugs has not completed yet.
Among these, naturally occurring prostaglandins having &agr;,&bgr;-unsaturated carbonyls in their five-membered rings, i.e., prostaglandins A and J, were reported to suppress DNA synthesis, suggesting their possible use as highly safe carcinostatics. Various derivatives thereof were synthesized (see JP-A 62-96438).
OBJECTS OF INVENTION
The main object of the present invention is to develop a compound having physiological activities such as a carcinostatic activity and to provide a method for producing the compound and a pharmaceutical composition containing the compound.
These and other objects as well as advantages of the present invention will be explained below with reference to the attached drawings.


REFERENCES:
patent: 6177592 (2001-01-01), Koyama et al.
patent: 0 984 011 (2000-03-01), None
patent: 5-310685 (1993-11-01), None
patent: 10-45618 (1998-02-01), None
patent: WO98/39291 (1998-09-01), None
Miyaguchi Shingo et al., “Relationship Between &agr;-Mannosidase and Natural Killer Activity and Glycopeptides of Peripheral Blood Mononuclear Cells in Patients with Liver Cirrhosis or Hepatocellular Carcinoma.” Keigo Igaku, vol. 69(2), pp. 335-346., 1992.

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