Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1990-11-30
1993-01-26
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
424 858, C07K 1300
Patent
active
051823675
ABSTRACT:
An 18kD protein (FLAP) has been isolated from rat and human cells which is necessary for production of leukotrienes from arachidonic acid in mammalian cells containing 5-lipoxygenase. The gene (cDNA) encoding for FLAP has also been produced.
REFERENCES:
Dixon et al. Nature 343:282-284 (1990).
Miller et al. Nature 343:278-281 (1990).
Dixon Richard A. F.
Evans Jillian F.
Fortin Rejean
Gauthier Jacques-Yves
Gillard John W.
DiPrima Joseph F.
Draper Garnette D.
Guest Shelly J.
Lopez Gabriel
Merck & Co. , Inc.
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