5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

Details 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs

1985-05-21

1986-09-09

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549459, A61K 31335, A61K 31557, C07D30700

Patent

active

046110054

ABSTRACT:
5,6-Epoxy-7-oxabicycloheptane substituted prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R.sup.1 is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, including all stereoisomers thereof.
The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

REFERENCES:
patent: 4143054 (1979-03-01), Sprague
patent: 4187236 (1980-02-01), Sprague
patent: 4220594 (1980-09-01), Sprague
patent: 4228180 (1980-10-01), Sprague
patent: 4254044 (1981-03-01), Sprague

Affiliated with

Also associated with

Rating

5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1015764