Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-11-30
1986-12-30
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544408, C07D24108, A61K 31495
Patent
active
046329242
ABSTRACT:
This invention relates to 5-(4-substituted)phenylpyrazinone compounds which have positive inotropic and vasodilator activity. One such compound is 5-(4-carboxamidophenyl)pyrazin-2(1H)-one.
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McOmie, ed., Protective Groups in Organic Chemistry, Plenum Press, New York, 1973, pp. 46-61.
Sheradsky et al., J.C.S. Perkin I:1296-1299 (1977).
Ohta et al., Hukusokan Kagaku Toronkai Kuen Yoshishu 8th:84-88 (1975), (Chem. Abstr. 84:164, 723Y).
Greene, ed., Protective Groups in Organic Synthesis, John Wiley and Sons, New York, 1981, pp. 222-249.
Emmett John C.
Slater Robert A.
Daniel Mark R.
Daus Donald G.
Lourie Alan D.
SmithKline Beckman Corporation
Teoli, Jr. William A.
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