5-(4-piperidinyl)dibenzothiazepine derivatives and 5-(4-piperidi

Details 5-(4-piperidinyl)dibenzothiazepine derivatives and 5-(4-piperidi 5-(4-piperidinyl)dibenzothiazepine derivatives and 5-(4-piperidi

1998-05-15

2000-05-16

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540550, A61K 3155, C07D26702, C07D28102

Patent

active

06063779&

ABSTRACT:
An objective of the present invention is to provide a compound that has antiarrhythmic activity. The present invention provides a compound of formula (I): ##STR1## wherein R.sup.1 and R.sup.2 each represent H, halogen or lower alkyl which may be substituted by halogen; A represents H, C3-6 cycloalkyl, phenyl which may be substituted by halogen, nitro, or lower alkoxy, a 5-membered or 6-membered heterocyclic ring which may contain N and/or S, --NR.sup.3 R.sup.4 (wherein R.sup.3 and R.sup.4 each represent H or lower alkyl which may be substituted by phenyl), or COR.sup.5 (wherein R.sup.5 represents OH, amino or lower alkoxy); Q represents S or O; m represents 0-18; and n represents 0-2, and pharmaceutically acceptable salts and solvates thereof.

REFERENCES:
patent: 3631052 (1971-12-01), Yale et al.
patent: 3796725 (1974-03-01), Yale et al.
patent: 4888335 (1989-12-01), Mohrbacher et al.

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