4H-pyrimido[2,1-a]isoquinolin-4-one derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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C07D47104, A61K 31505

Patent

active

046615920

ABSTRACT:
This invention relates to a class of novel 4H-pyrimido[2,1-a]isoquinoline derivatives. The invention further relates to pharmaceutical compositions containing such 4H-pyrimido[2,1-a]isoquinoline-4-one derivatives and to the use of such compounds and compositions as anorectic agents. In particular, the novel 4H-pyrimido[2,1-a]isoquinoline-4-one derivatives are effective anorectic agents when administered orally.

REFERENCES:
patent: 4127720 (1978-11-01), Juby et al.
patent: 4348396 (1982-09-01), Kierstead et al.
Tilley, et al., J. Med. Chem., vol. 26, No. 11, pp. 1638-1642 (1983).

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