Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-12-12
2006-12-12
Jiang, Shaojia Anna (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S323000, C514S329000, C514S616000, C536S004100, C536S017200, C536S017300, C536S018500, C536S027100, C536S027200, C536S027600, C536S027700, C544S264000, C544S350000, C549S013000
Reexamination Certificate
active
07148223
ABSTRACT:
Compounds represented by the formula 1:A is selected from the group consisting ofwherein each R individually is H or acyl, Y is X, N3, NH2, monoalkylamino, or dialkylamino; Z is O or S; andX is selected from the group consisting of hydrogen, halo, hydroxy, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, thioaryl, thioalkyl, allylamino, cyano and nitro; tautomers thereof; and pharmaceutically acceptable salts thereof are provided along with methods for their fabrication. Various of these compounds can be used as anticancer agents, or antiviral agents or to inhibit DNA replication.
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“Synthesis and biological activity of certain 4′-thio-D-arabinofuranosylpurine nucleosides.” by Secrist III et al., J. Med. Chem. 41. pp. 3865-3871, 1988.
“Synthesis of (−(4-thioxylofuranosyl) adenine via a novel glycosylation reaction.” by Hartsel et al., Tetrahedron Letters, 39, pp. 205-208, 1998.
Montgomery John A.
Secrist, III John A.
Tiwari Kamal N.
Connolly Bove & Lodge & Hutz LLP
Khare Devesh
Southern Research Institute
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