Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1979-11-05
1982-09-14
Sutto, Anton H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
2603265R, 2603265C, 2603265CA, 560 56, 564180, A61K 3140, C07D20726
Patent
active
043495613
ABSTRACT:
Novel 4-substituted-3-hydroxy-3-pyrroline-2,5-diones are disclosed which inhibit glycolic acid oxidase and thus are useful in the treatment and prevention of calcium oxalate kidney stone formation. A novel process for their preparation is also disclosed.
REFERENCES:
patent: 3340263 (1967-09-01), Stachella
Ligo et al., "Arch. Biochem. Biophys", vol. 154, (1973), pp. 68-75.
Harlay, "J. Pharm. Chim.", vol. 24, (1936), pp. 537-548.
Skinner et al., "J. Am. Chem. Soci.", vol. 73, (1951), p. 2230.
Skinner, "JACS", vol. 70, (1948), p. 4011.
Cragoe, Jr. Edward J.
Rooney Clarence S.
Williams Haydn W. R.
Merck & Co. , Inc.
Speer Raymond M.
Sudol, Jr. Michael C.
Sutto Anton H.
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