4-quinolone derivatives having anti-inflammatory, anti-allergic,

Details 4-quinolone derivatives having anti-inflammatory, anti-allergic, 4-quinolone derivatives having anti-inflammatory, anti-allergic,

1985-09-27

1987-12-08

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546153, 560 43, 560 51, A61K 3147, C07D21548

Patent

active

047118989

ABSTRACT:
4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.

REFERENCES:
patent: 2785165 (1957-03-01), Schock
patent: 4049715 (1977-09-01), Bell
patent: 4476132 (1984-10-01), Goschke et al.
Schock, J. Am. Chem. Soc., vol. 79, pp. 1672-1675 (1957).
Andersag, et al., Chemical Abstracts, vol. 48, 12183h (1954).
Joh, et al., Chemical Abstracts, vol. 73, 45294x, 45295y (1970).
DE No. 2,806,879 (cf. Chem. Abstr. 91, 211281j).
EP No. 62,001 (cf. Chem. Abstr. 98, 160599d).

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