4-phenylpiperdine agents for treating cns disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 514316, 514317, 514327, 514330, 540590, 546189, 546208, 546217, 546225, 546227, 546236, 546240, A61K 31445, C07D21132, C07D40102

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active

053648676

ABSTRACT:
4-Phenylpiperidines of the formula ##STR1## wherein R.sub.1 is hydrogen, hydroxy or lower-alkoxy;

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Leander, J. D. & D. M. Zimmerman, "Antagonism of Bremazocine-Induced Urinaation as a Test for Kappa-Opioid Receptor Antagonists within the Phenylpiperidine Series" Drug Devel. Res. 4:421-427 (1984).
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