4-phenyl-1,3-benzodiazepines and 2-amino-.alpha.-phenylphenethyl

Details 4-phenyl-1,3-benzodiazepines and 2-amino-.alpha.-phenylphenethyl 4-phenyl-1,3-benzodiazepines and 2-amino-.alpha.-phenylphenethyl

1992-10-08

1993-11-09

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514615, 514646, A61K 3116, A61K 31135

Patent

active

052603393

ABSTRACT:
Novel 4-phenyl-1,3-benzodiazepines and 2-amino-.alpha.-phenylphenethylamines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants. The 2-amino-.alpha.-phenylphenethylamines are useful as anticonvulsant and neuroprotective agents.

REFERENCES:
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patent: 4002611 (1977-01-01), Yamamoto et al.
patent: 4822914 (1989-04-01), Merten et al.
H. G. O. Holck, et al., J. Am. Pharm. Assoc., 39, 354 (1960).
H. Lund, Acta. Chem., Scand., 21, 2525 (1967).
K. Ogiu, Chem. Abs., 54 18426 (1960).
D. E. Ames, et al., J. Chem. Soc., (c), 796 (1969).

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