4-hydroxyphenyl acetic acid

Details 4-hydroxyphenyl acetic acid 4-hydroxyphenyl acetic acid

1991-07-29

1992-09-08

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 6501

Patent

active

051459949

ABSTRACT:
A process for the preparation of 4-hydroxyphenyl acetic acid of the formula I, an important raw material for the preparation of pharmaceutically active substances, from sodium-4-hydroxymandalate monohydrate comprising reducing the sodium-4-hydroxymandalate monohydrate with a reducing agent consisting of stoichiometric quantity of a phosphorus (III) compound and catalytic or stoichiometric quantity of sulphur dioxide or equivalent salt thereof in a solvent at 60.degree.-120.degree. C. and at ambient to 5 atmospheres pressures.

REFERENCES:
CA 104(3):19415b 1985.

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