Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-06-27
1979-03-20
Waltz, Thomas
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260553C, 424322, C07C12717, A61K 3117
Patent
active
041453638
ABSTRACT:
There are disclosed novel 4-substituted amino-.alpha.-aminomethylbenzyl alcohol derivatives represented by the formula: ##STR1## wherein X represents a halogen atom; Y represents a hydrogen atom or a halogen atom; R.sub.1 represents a lower alkyl group, a carbamoyl group, a mono- or di-lower alkyl-substituted carbamoyl group, a phenyl-substituted carbamoyl group, a lower alkoxycarbonyl group, a lower alkoxy-substituted lower alkoxycarbonyl group, a phenyl-substituted lower alkoxycarbonyl group, or a cycloalkyloxycarbonyl group; and R.sub.2 represents a lower alkyl group, a cycloalkyl group, or the group shown by the ##STR2## wherein R.sub.3 represents a hydrogen atom or a lower alkyl group and R.sub.4 represents a hydrogen atom, a hydroxy group, or a lower alkoxy group and the pharmaceutically acceptable nontoxic salts thereof.
These compounds are antiasthmatic agents useful for the prophylaxis and treatment of asthma.
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Ida Hisashi
Mase Toshiyasu
Murakami Masuo
Murase Kiyoshi
Takahashi Kozo
Waltz Thomas
Yamanouchi Pharmaceutical Co. Ltd.
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