4-alkoxy-pyrido[2,3-d]pyrimidine derivatives

Details 4-alkoxy-pyrido[2,3-d]pyrimidine derivatives 4-alkoxy-pyrido[2,3-d]pyrimidine derivatives

1985-10-16

1987-07-21

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544279, A61K 31435, C07D47104

Patent

active

046818820

ABSTRACT:
4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation.
For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arteriosclerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality.

REFERENCES:
patent: 4361700 (1982-11-01), Purcell et al.
patent: 4560753 (1985-12-01), Lesher et al.
Gorlitzer et al., Arch. Pharm. (Weinheim) vol. 314, pp. 938-949 (1981).

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