4,5-Didehydro-6-oxo-2-aryl-methoxymethyl-3.alpha.-tetrahydropyra

Details 4,5-Didehydro-6-oxo-2-aryl-methoxymethyl-3.alpha.-tetrahydropyra 4,5-Didehydro-6-oxo-2-aryl-methoxymethyl-3.alpha.-tetrahydropyra

1977-04-04

1978-04-11

Jaisle, Cecilia M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30932

Patent

active

040838544

ABSTRACT:
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 (11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.

REFERENCES:
patent: 4032542 (1977-06-01), Kelly
patent: 4048194 (1977-09-01), Nelson

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