4,4,5,5-Tetradehydro-PGE.sub.1 analogs

Details 4,4,5,5-Tetradehydro-PGE.sub.1 analogs 4,4,5,5-Tetradehydro-PGE.sub.1 analogs

1975-10-02

1977-03-22

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260211R, 2602472R, 260268R, 26029365, 2603262, 260408, 260413, 2604299, 260439R, 260448R, 2604488R, 260468D, 260473A, 2605011, 26050115, 26050117, 2605012, 260514D, 260520B, 260613D, 260617F, 260624R, 424305, 424308, 424317, 424318, 536 18, C07C17700

Patent

active

040136957

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which there is a triple bond between C-5 and C-6 or C-4 and C-5. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 3933889 (1970-01-01), Magerlin

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