Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-11
2006-07-11
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S269400
Reexamination Certificate
active
07074815
ABSTRACT:
The present invention provides new 4-[3,5-bis-(2-hydroxy-phenyl)-[1,2,4]triazol-1-yl]-benzoic acid derivatives which can be used in the treatment of diseases which cause an excess of metal in the human or animal body or are caused by it.
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patent: 6596750 (2003-07-01), Lattmann et al.
patent: 6723742 (2004-04-01), Lattmann et al.
patent: WO 97/49395 (1997-12-01), None
Heinz, et al. 4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]-benzoic acid: A Novel Efficient and Selective Iron (III) Complexing Agent. Angew. Chemie Int. Ed., vol. 38, No. 17, pp. 2568-2570 (1999).
Heinz, U. et al., “4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]-benzoic Acid: A Novel Efficient and Selective Iron(III) Complexing Agent,” Angew. Chemie Int. Ed., vol. 38, No. 17, pp. 2568-2570 (1999).
Rouan M.C., “Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection,” Journal of Chromatography B, vol. 755, pp. 203-213 (2001).
Lattmann Rene
Waldmeier Felix
Chung Susannah L.
Jackson Oona A.
Novartis AG
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