Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1995-05-31
1996-04-30
Daus, Ronald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C07D 3714
Patent
active
055125719
ABSTRACT:
Diastereomeric intermediate salts of formulae (IIIa) or (IIIb) ##STR1## are prepared.
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J. Org. Chem. 1991, 56, 1963-1966, An Enantioselective synthesis of SK&F 93505, A Key Intermediate for Preparing Cardiotonic Agents by Franklin F. Owings, Margaret Fox, Conrad J. Kowalski, and Neil H. Baine.
"Synthesis and Biological Activity of Four Stereoisomers of 6- 4- 3- 2 Hydroxy-3- 4- 2-(Cyclopropylmethoxy)ethyl!phenoxyl!propl!amino !-propionamide!phenyl!-5-methyl-4,5-dihydro-3(2H)-pyridazinone, a Combined Vasodilator and .beta.-Adrenoceptor Antagonist", W. Howson et al., J. Med. Chem. 1988, vol. 31, pp. 352-356.
Backstrom Reijo
Haarala Jorma
Haikala Heimo
Honkanen Erkki
Nore Pentti
Daus Ronald G.
Orion-yhtyma Oy
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