4-(1,2-benzisoxazolyl)piperidine antipsychotic agents

Details 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents

1992-06-22

1994-01-04

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514321, 514326, 546157, 546158, 546198, 546209, A61K 3147, C07D21520

Patent

active

052760405

ABSTRACT:
Certain 1-substituted 4-(1,2-benzisoxazolyl)-piperidine compounds exhibit neuroleptic activity and are useful in the treatment of psychosis and anxiety.

REFERENCES:
patent: 4458076 (1984-07-01), Strupczewski
patent: 4558060 (1985-12-01), Caignard et al.
patent: 4619932 (1986-10-01), Banno
patent: 4801595 (1989-01-01), Archibald
patent: 4831031 (1989-05-01), Lowe et al.
Strupczewski et al., J. Med. Chem., 1985, vol. 28, No. 6, pp. 761-769.
Leysen et al., J. Pharm. Exp. Ther., 247, No. 2, pp. 661-670, 1988.
Janssen et al., J. Pharm. Exp. Ther., 244, No. 2, pp. 685-693, 1988.

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