3-substituted methyl-2,3-dihydroimidazo[1,2-C] quinazoline deriv

Details 3-substituted methyl-2,3-dihydroimidazo[1,2-C] quinazoline deriv 3-substituted methyl-2,3-dihydroimidazo[1,2-C] quinazoline deriv

1992-10-14

1994-08-23

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544250, 544285, 544286, A61K 31505, C07D48704

Patent

active

053408144

ABSTRACT:
The present invention provides a novel series of 3-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazoline compounds. These compounds are found useful as an active ingredient for the treatment of hypertension and dysuria.

REFERENCES:
patent: 5120736 (1992-06-01), Houziaux et al.
patent: 5128338 (1992-07-01), Bourguignon et al.
patent: 5158953 (1992-10-01), Chern et al.
Medicinal Chemistry (2nd Ed.) by Alfred Burger (Interscience Publishers), pp. 72-78 (1960).
Ji-Wang Chern, "Studies on Quinazolinones, 3:1 Novel and Efficient . . . ", Bioorganic & Medicinal Chemistry Letters, vol. 1, No. 11, pp. 571-574, 1991.
N. Seki, et al., "Electrical and Mechanical Properties . . . ", Br. J. Pharmacol. (1988), 93, 702-714.
Yamanouchi et al., An article from Drug of the Future (1989), p. 400.

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