3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr

Details 3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr 3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr

1976-06-28

1978-04-11

Rotman, Alan L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260295R, C07D21355

Patent

active

040838501

ABSTRACT:
Novel compounds useful as hypotensive agents are presented having the general formula I ##STR1## wherein R.sub.1 represents a lower aliphatic acyl group, a straight or branched chain alkyl or alkenyl group or an aralkyl group of the general formula ##STR2## wherein R.sub.2 represents hydrogen, a lower alkyl group or a halogen atom. Furthermore, new therapeutic compositions of matter are also described incorporating the above novel 3-substituted-2(1H)pyridone-6-carboxylic acids (I) as an active ingredient with carriers and showing uses as hypotensive agents. These new compounds of the formula I are prepared either by reacting D-glucaro-.delta.-lactam or its salt with an acid anhydride or by reacting 3-hydroxy-2(1H)pyridone-6-carboxylic acid with an acyl anhydride or alkyl halide, aralkyl halide and an alkenyl halide.

REFERENCES:
patent: 3956337 (1976-05-01), Niwa et al.
Shukla et al., Chem. Abstracts, vol. 81 (1), item no. 1160m, July 8, 1974.

Affiliated with

Also associated with

Rating

3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-Substituted-2(1H)pyridon-6-carboxylic acids and process for pr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-988563