3-Quinuclidinyl amino-substituted biaryl derivatives

Details 3-Quinuclidinyl amino-substituted biaryl derivatives 3-Quinuclidinyl amino-substituted biaryl derivatives

2007-12-18

2007-12-18

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252040, C514S255050, C514S256000, C514S305000, C540S557000, C544S238000, C544S333000, C544S405000, C546S133000

Reexamination Certificate

active

11015158

ABSTRACT:
Compounds of formula (I)wherein A is N or N+—O−; n is 0, 1, or 2; Y is O, S, —NH—, and —N-alkyl-; Ar1is both 6-membered aromatic rings; Ar2is 5- or 6-membered aromatic rings with a —NR8R9group, as defined herein. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

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