3-Pyridylaminoalkyleneamino-4-amino-1,2,5-thiadiazole-1-oxides,

Details 3-Pyridylaminoalkyleneamino-4-amino-1,2,5-thiadiazole-1-oxides, 3-Pyridylaminoalkyleneamino-4-amino-1,2,5-thiadiazole-1-oxides,

1986-03-12

1987-09-08

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514342, 546256, 546277, A61K 3144, A61K 3141, C07D41712, C07D41714

Patent

active

046924566

ABSTRACT:
New 3,4-diamino-1,2,5-thiadiazole oxide derivatives which are histamine H.sub.1 -antagonists. A specific compound of this invention is 3-[3-(N-propyl-N-2-pyridylamino)-propylamino]-4-(4-pyridylmethyl)amino-1,2 ,5-thiadiazole-1-oxide.

REFERENCES:
patent: 4374248 (1983-02-01), Crenshaw et al.
patent: 4394508 (1983-07-01), Crenshaw et al.
patent: 4532246 (1985-07-01), Ife

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