3-propenylcephem derivative

Details 3-propenylcephem derivative 3-propenylcephem derivative

1990-01-11

1991-04-09

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50124, A61K 31545

Patent

active

050066498

ABSTRACT:
A 3-propenylcephem derivative of the following formula: ##STR1## wherein R.sub.1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcephem derivative; and Process for the preparation of the intermediate.

REFERENCES:
patent: 4486586 (1984-12-01), Narita et al.
patent: 4631274 (1986-12-01), Takaya et al.
patent: 4751295 (1988-06-01), Oka et al.
patent: 4761410 (1988-08-01), Takaya et al.

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