Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-01-11
1992-02-18
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514202, 514203, 540222, 540225, 540226, C07D50124, A61K 31545
Patent
active
050894919
ABSTRACT:
A 3-propenylcephem derivative of the following formula: ##STR1## wherein R.sub.1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcephem derivative; and Process for the preparation of the intermediate.
REFERENCES:
patent: 4486586 (1984-12-01), Narita et al.
patent: 4520193 (1983-05-01), Berger et al.
patent: 4751295 (1988-06-01), Oka et al.
patent: 4761410 (1988-08-01), Takaya et al.
Kai Yasunobu
Kamiya Takashi
Katsu Kanemasa
Kitoh Kyosuke
Komatu Yuuki
Eisai Co. Ltd.
Rizzo Nicholas S.
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