3-phenylthiomethylstyrene derivative, process for preparing the

Details 3-phenylthiomethylstyrene derivative, process for preparing the 3-phenylthiomethylstyrene derivative, process for preparing the

1986-07-28

1989-08-01

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514424, 514473, 514570, 514618, 514713, 548321, 548361, 548543, 549323, 558401, 560 9, 560 11, 560 12, 560 13, 562426, 562429, 562430, 564162, A61K 31085, A61K 31095, A61K 3104, A61K 31135, A61K 3119, A61K 31215, A61K 31275, A61K, A61K, A61K 3140, A61K 3141, C07D23108, C07D20712, C07D30732, C07C14940, C07C147107, C07C14367, C07C14713, C07C14711

Patent

active

048534030

ABSTRACT:
A 3-phenylthiomethylstyrene derivative having the general formula (1): ##STR1## or salt thereof with a base, when X is hydroxyl group, R.sup.1 is hydrogen atom or R.sup.2 is hydrogen atom, a process for preparing the 3-phenylthiomethylstyrene derivative (1), and an antiallergic agent and a tyrosinekinase inhibiting agent containing the 3-phenylthiomethylstyrene derivative (1) as an effective component. The compound (1) of the present invention is a useful intermediate for preparing various organic compounds, and has excellent antiallergic and tyrosinekinase inhibiting activities.

REFERENCES:
patent: Re29467 (1977-11-01), Nussim et al.
patent: 3940422 (1976-02-01), Harita et al.
Chemische Berichte, 95, 483-486 (1962).

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