3-oxa-5-fluoro-carbacyclins, their preparation and use as medici

Details 3-oxa-5-fluoro-carbacyclins, their preparation and use as medici 3-oxa-5-fluoro-carbacyclins, their preparation and use as medici

1991-06-10

1992-10-20

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 514623, 560119, 562501, 564188, C07C17700, A61K 31557

Patent

active

051570424

ABSTRACT:
Carbacyclin derivatives of Formula I ##STR1## wherein R.sub.1 is OR.sub.2, wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, ##STR2## or a heterocyclic residue; or R.sub.1 is NHR.sub.3 wherein R.sub.3 is an acid residue (acyl) or R.sub.2 ;

REFERENCES:
patent: 4306075 (1981-12-01), Aristaff
patent: 4423067 (1983-12-01), Skuballa
patent: 4618626 (1988-10-01), Skuballa

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