3-methylene-4-androsten-17-ones, process for their production an

Details 3-methylene-4-androsten-17-ones, process for their production an 3-methylene-4-androsten-17-ones, process for their production an

1988-04-29

1990-05-15

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514178, 552526, 552632, 552636, 552615, 540114, A61K 3156, C07J 100

Patent

active

049258346

ABSTRACT:
A 3-methylene-4-androsten-17-one of formula I ##STR1## wherein R.sub.a represents a hydrogen atom or a saturated or unsaturated straight-chain or branched-chain, optionally substituted alkyl radical with 1-6 carbon atoms, in which R.sub.a is in the alpha- or beta-position, and

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patent: 3450720 (1969-06-01), La Lancette
patent: 4289762 (1981-09-01), Metcalf et al.
patent: 4473564 (1984-09-01), de Winter
patent: 4546098 (1985-10-01), Fishman et al.
Brodie, A. M., et al., "Studies on the Mechanism of Estrogen Biosynthesis in the Rat Ovary," J. Steroid Biochem., 1976, vol. 7, pp. 787-791.
Chemical Abstracts, vol. 105, Nr. 9, 1, Sep. 1, 1986.

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