3-Heterothio[(thioalkyl)thioacetyl]cephalosporanic derivatives

Details 3-Heterothio[(thioalkyl)thioacetyl]cephalosporanic derivatives 3-Heterothio[(thioalkyl)thioacetyl]cephalosporanic derivatives

1974-10-11

1977-01-18

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, 2603322A, 2603472, 260470, 260481R, 260515M, 260526S, 260544S, 260544Y, C07D50150

Patent

active

040038939

ABSTRACT:
3-Heterothio[(thioalkyl)thioacetyl]cephalosporin derivatives which have the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl)silyl, a salt forming ion, or the group ##STR2## R.sub. 1 is hydrogen, lower alkyl, phenyl, thienyl of furyl; R.sub.2 and R.sub.6 each is hydrogen or lower alkyl; R.sub.3 and R.sub.5 each is lower alkyl, phenyl or phenyl-lower alkyl; and R.sub.4 is a five- or six-membered nitrogen and/or sulfur or oxygen-containing ring system; are useful as antibacterial agents.

REFERENCES:
Lewis et al., Antimicrobial Agents & Chemeotherapy 1968 pp. 109-114 (1969).

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