3-heteroaryl-3, 5-dihydro-4-oxo-4H-pyridazino[4,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S115000, C544S234000, C514S234800, C548S492000

Reexamination Certificate

active

07109194

ABSTRACT:
The invention concerns compounds of general formula (I), wherein: X represents a hydrogen or halogen atom; R1represents a hydrogen atom or a (C1–C4)alkyl group; R2and R3, represent each, independently of each other, a hydrogen atom or a (C1–C4)alkyl group, or R2and R3form, with the atom which bears them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl, pyridazinyl type, the heteroaromatic group may represent one or several halogen atoms and/or one or several (C1–C4)alkyl, (C1–C4)alkoxyl groups; in the form of bases, addition salts to acids, solvates or hydrates. The invention also concerns pharmaceutical compositions containing same, methods for preparing same and synthesis intermediates

REFERENCES:
patent: 6075021 (2000-06-01), Evanno et al.
patent: 6451795 (2002-09-01), Marguet et al.
patent: WO 98 15552 (1998-04-01), None
patent: WO 00 44751 (2000-08-01), None
patent: WO 02 08229 (2002-01-01), None
Lacapere et al. Steroids 68 (2003) 569-585.

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