3-Fluorobenzodiazepines

Material or article handling – Apparatus particularly adapted for charging or discharging a... – Including one or more movable sites

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424263, 260239BD, 2602393D, 546328, 546371, 546315, 546316, 546323, 564195, 564211, C07D24324, A61K 3155

Patent

active

042320160

ABSTRACT:
3-Fluoro-2,3-dihydro-1H-1,4-benzodiazepin-2-ones of the formula ##STR1## wherein R.sup.1 is H, alkyl or fluorinated alkyl of 1-4 carbon atoms and up to 9 fluorine atoms or cycloalkylalkyl of 4-8 carbon atoms; R.sup.2 is phenyl; monohalophenyl or pyridyl; R.sup.3 is F, Cl, Br or NO.sub.2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.

REFERENCES:
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patent: 3296249 (1967-01-01), Bell
patent: 3296251 (1967-01-01), Bell et al.
patent: 3299053 (1967-01-01), Archer et al.
patent: 3371085 (1968-02-01), Reeder et al.
patent: 3429874 (1969-02-01), Topliss et al.
Sternbach et al., "Some Aspects of Structure-Activity Relationship in Psychotropic Agents of the 1,4-Benzodiazepine Series CSIR New Delhi, India (1966).

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