3-carbonyl-4-amino-8-substituted quinoline compounds useful in i

Details 3-carbonyl-4-amino-8-substituted quinoline compounds useful in i 3-carbonyl-4-amino-8-substituted quinoline compounds useful in i

1990-08-07

1992-01-21

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514313, 544128, 544363, 546159, 546160, 546161, 546162, C07D21542, A61K 3147

Patent

active

050828410

ABSTRACT:
Aminoquinoline derivatives are described as inhibitors of the H.sup.+ K.sup.+ ATPase enzyme useful in the treatment of gastric acidity. A compound of the invention is 3-butyryl-4-(2-methylphenylamino)-8-(3-dimethylaminopropoxy)quinoline.

REFERENCES:
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patent: 4343804 (1982-08-01), Munson, Jr. et al.
patent: 4789678 (1988-12-01), Effland et al.
patent: 4806549 (1989-02-01), Ife et al.
patent: 4806550 (1989-02-01), Ife et al.
patent: 4808598 (1989-02-01), Canfield et al.
patent: 4935431 (1990-06-01), Ife et al.
patent: 5006535 (1991-01-01), Ife et al.
Hanifin et al., J. Med. Chem., 1969, 12, 1096.

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