3',6-diisopentenyl-2',4'-dihydroxy-5,7-dimethoxy-isoflavan and r

Details 3',6-diisopentenyl-2',4'-dihydroxy-5,7-dimethoxy-isoflavan and r 3',6-diisopentenyl-2',4'-dihydroxy-5,7-dimethoxy-isoflavan and r

1984-10-01

1987-01-27

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514454, 549406, A61K 3135

Patent

active

046394664

ABSTRACT:
3',6-Diisopentenyl-2',4'-dihydroxy-5,7-dimethoxyisoflavan has been isolated from Glycyrrhiza uralensis Fisch. It has been found that this compound and other related compounds are potent stimulators of benzodiazepine receptors and thereby useful as effective anxiolytic agents. Furthermore, these compounds have been found to be potent antidotes of avermectin.

REFERENCES:
Ingham, Progress in the Chemistry of Organic Natural Products, 43, 160-181 (1983).
Takashi Kinoshita et al., Chem. Pharm. Bull, 26(1), 141-143 (1978) "A New Isoflavone from Licorice Root".

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