3,4-dihydro-2H-1-benzopyran derivatives

Details 3,4-dihydro-2H-1-benzopyran derivatives 3,4-dihydro-2H-1-benzopyran derivatives

1986-09-15

1988-11-29

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549405, A61K 3135, C07D31158

Patent

active

047882140

ABSTRACT:
The invention relates to compounds of the formula ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2 is hydrogen or halogen; R.sup.3, R.sup.4 and R.sup.5 are hydrogen, acyl or lower alkyl; R.sup.6 and R.sup.7, independently, are hydrogen or lower alkyl; X is alkylene.sub.3-7 ; and n is an integer of zero to four; provided that only one of R.sup.3, R.sup.4 or R.sup.5 can be acyl;
enatiomers thereof, and, when R.sup.7 is hydrogen, salts thereof with pharmaceutically acceptable bases.
The compounds of formulas I and II are useful as agents for the treatment of allergic conditions.

REFERENCES:
patent: 3629290 (1971-12-01), Cairns et al.
patent: 4006245 (1977-02-01), Augustein et al.
patent: 4281008 (1981-07-01), Chamberlain et al.
patent: 4546194 (1985-10-01), Miyano et al.
Some New Coumarins and Chromones and Their Ultraviolet Absorption Spectra-C. R. Jacobson et al, J. Org. Chem. 18, 1117 (1953).
Pharmacologically Active 4-Oxo-4H-Chromen-2-Carboxylic Acids, Part II, The Synthesis of 4-Oxo-4H-Chromen-2-Carboxylic Acids Containing a Fused Imidazole or Oxazole Ring--A. O. Fitton et al, J. Chem. Soc. (c) 1970, pp. 2518-2522.
Benzopyrones Part II, 7-Hydroxy-4-Oxochromen-2-Carboxylic Acid and Some of Its Derivatives--G. Barker et al, J. Chem. Soc. (c) (1970), pp. 2609-2612.

Affiliated with

Also associated with

Rating

3,4-dihydro-2H-1-benzopyran derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3,4-dihydro-2H-1-benzopyran derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3,4-dihydro-2H-1-benzopyran derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-363870