3-(4-benzyloxyphenyl) propanoic acid derivatives

Details 3-(4-benzyloxyphenyl) propanoic acid derivatives 3-(4-benzyloxyphenyl) propanoic acid derivatives

2004-12-24

2008-11-25

Solola, Taofiq A (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

C562S407000

Reexamination Certificate

active

07456218

ABSTRACT:
The present invention provides a novel compound represented by the formula (I) wherein each symbol is as defined in the specification, a salt thereof and a prodrug thereof having a superior GPR40 receptor function modulating action, which can be used as an insulin secretagogue, an agent for the prophylaxis or treatment of diabetes and the like. They unexpectedly show superior GPR40 receptor agonist activity, and also show superior properties as a pharmaceutical product, such as stability and the like. Thus, they can be safe and useful pharmaceutical agents for the prophylaxis or treatment of GPR40 receptor related diseases in mammals.

REFERENCES:
patent: 2003-261491 (2003-09-01), None
patent: 97/31907 (1997-09-01), None
patent: 99/11255 (1999-03-01), None
patent: 00/64876 (2000-11-01), None
patent: 01/00603 (2001-01-01), None
patent: 01/55085 (2001-08-01), None
patent: 01/79150 (2001-10-01), None
patent: 02/053547 (2002-07-01), None
patent: 02/083616 (2002-10-01), None
patent: 02/092590 (2002-11-01), None
patent: 02/100813 (2002-12-01), None
patent: 03/018553 (2003-03-01), None
patent: 03/084916 (2003-10-01), None
patent: 03/099793 (2003-12-01), None
patent: 2004/000315 (2003-12-01), None
patent: 2004/041266 (2004-05-01), None
patent: 2004/091604 (2004-10-01), None
Y. Itoh et al., “Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40”, Nature, vol. 422, No. 6928, pp. 173-176, Mar. 13, 2003.

Affiliated with

Also associated with

Rating

3-(4-benzyloxyphenyl) propanoic acid derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-(4-benzyloxyphenyl) propanoic acid derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-(4-benzyloxyphenyl) propanoic acid derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4036478