3,3-dialkyl-and 3,3-alkylene-indoline derivatives, processes for

Details 3,3-dialkyl-and 3,3-alkylene-indoline derivatives, processes for 3,3-dialkyl-and 3,3-alkylene-indoline derivatives, processes for

1985-01-17

1986-11-11

Lesmes, George F.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548411, 548490, 514415, C07D20908, C07D20954, A61K 3140

Patent

active

046223363

ABSTRACT:
3,3-Dialkyl- or 3,3-alkylene-indolines which are unsubstituted at the 1- and 2-positions and which are substituted at the 4- or 6-position by an optionally etherified hydroxy group or substituted at the 5- or 7-position by an etherified hydroxy group, as well as their physiologically-hydrolyzable and -acceptable esters. The said indolines and esters as well as their pharmaceutically acceptable acid addition salts possess analgesic activity.

REFERENCES:
patent: 4159271 (1979-06-01), Sano et al.
patent: 4216220 (1980-08-01), Nakagawa et al.
patent: 4255333 (1981-03-01), Opgenorth et al.
patent: 4307235 (1981-12-01), Ong et al.
patent: 4345081 (1982-08-01), Ong et al.
patent: 4408050 (1983-10-01), Ong et al.
Z. Obsc. Chim. 23 (1983), P. Kolosow et al, English Edition pp. 1879 to 1883.
Dopp et al, Chem., Ber. 111, 3806 (1978).

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