3-(1-Pyrazolyl)-pyridazine derivatives

Details 3-(1-Pyrazolyl)-pyridazine derivatives 3-(1-Pyrazolyl)-pyridazine derivatives

1978-06-09

1981-02-17

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

424250, 42424854, 42424855, 42424853, 544114, C07D40304, C07D40114, C07D40514, A61K 3150

Patent

active

042516587

ABSTRACT:
3-(1-Pyrazolyl)-pyridazine derivatives of the formula I, or pharmaceutically acceptable acid addition salts thereof, which decrease high blood pressure and inhibit catabolism or prostaglandins, ##STR1## wherein R.sup.1 is hydrogen or C.sub.1-4 alkyl,

REFERENCES:
patent: 3367936 (1968-02-01), Koppe et al.
Shirakawa et al., Chem. Abs. 60, 12009-12011, (1964).
Elguero et al., Bul. Chem. Soc., France, 1970, 1346.
Twomey, Chem. Abs., 81, 3864t, (1974).
Elguero et al., Bull. Soc. Chim. Fr., 1970, p. 1346.
Shirakawa et al., Chem. Abs., 60, 12010, (1963).
Karpova et al., Chem. Abs., 81, 3864, (1974).

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