Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-08-29
2006-08-29
Habte, Kahsay (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S238000
Reexamination Certificate
active
07098210
ABSTRACT:
The invention refers to novel 2H-pyridazine-3-one derivatives of the formula I, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient. The novel compounds possess neuroleptic effect and can be used, primarily, for the treatment of schizophrenia. In formula I, R stands for a hydrogen atom or a C1-4, alkyl group, X and Y represent, independently, a hydrogen atom, a halogen atom or a group of the formula II, with the proviso that one of X and Y means always a group of the formula II, and then the other one stands for a hydrogen atom or a halogen atom, wherein in formula II n has a value of 1 or 2.
REFERENCES:
patent: 5034391 (1991-07-01), Blaschke et al.
patent: 5736558 (1998-04-01), Foguet et al.
Strappaghetti et al, “New 3 (2H) -pyridazinone derivatives: synthesis and affinity towards alpha1AR subtypes and 5HT1A receptors”, European journal of medicinal chemistry editions scientifique elsevier, Paris, FR, vol. 32, No. 4, 1997, pp. 339-342.
Barkóczy József
Egyed András
Gacsályi István
Kótay Nagy Péter
Kovács Anikó Miklósné
Birch & Stewart Kolasch & Birch, LLP
Egis Gyógyszergyár Rt.
Habte Kahsay
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