25501, a human transferase family member and uses therefor

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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C435S006120, C435S252300, C435S325000, C536S023200

Reexamination Certificate

active

06929938

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated 25501 nucleic acid molecules, which encode novel transferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 25501 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 25501 gene has been introduced or disrupted. The invention still further provides isolated 25501 proteins, fusion proteins, antigenic peptides and anti-25501 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
patent: WO 01/57182 (2001-08-01), None
patent: WO 02/074961 (2002-09-01), None
Strausberg, R.L., “Homo sapiens THUMP domain containing 2, mRNA (cDNA clone MGC:2454 IMAGE:2961526), complete cds” Jun. 29, 2004 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jan. 10, 2005]. Retrieved from the internet: URL: http://www.ncbi.nim.nih.gov. GenBank Accession No. BC004163.
Zhang, Y., et al., “Homo sapiens clone RP11-288L6 SAM-dependent methyltransferase mRNA, complete cds,” Oct. 25, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jan. 10, 2005]. Retrieved from the internet: URL: http://www.ncbi.nim.nih.gov. GenBank Accession No. AF380578.
Zhang, Y., et al., “Homo sapiens clone RP11-288L6 SAM-dependent methyltransferase mRNA, complete cds,” Oct. 25, 2001 (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Jan. 10, 2005]. Retrieved from the internet: URL: http://www.ncbi.nim.nih.gov. GenBank Accession No. AF380577.

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