25-Alkylcholest-5-ene-3.beta.,22-diols and esters thereof

Details 25-Alkylcholest-5-ene-3.beta.,22-diols and esters thereof 25-Alkylcholest-5-ene-3.beta.,22-diols and esters thereof

1978-07-28

1980-05-27

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

042050049

ABSTRACT:
25-Alkylcholest-5-ene-3.beta.,22-diols and esters thereof adapted to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase are disclosed.

REFERENCES:
patent: 4006172 (1977-02-01), Salmond
J. Biol. Chem. (1974) No. 249, Article by Kandutsch et al., pp. 6057, etc.
J. Chem. Res. (1977) Article by Nagana et al., pp. 2522, etc.
Md. Cryst. Lig. Cryst. (1971) p. 255, Article by Elser et al.
J. Biol. Chem. (1974) 249, Article by Brown et al., pp. 7306 etc.
C.A. vol. 85 (1976) Pars. 91,024(e).

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