Methods to identify immunomodulators using cognate interaction o

Details Methods to identify immunomodulators using cognate interaction o Methods to identify immunomodulators using cognate interaction o

1996-06-18

1999-08-10

Grimes, Eric

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

435 6, 435 78, 435 29, C12Q 102, C12Q 148, C12Q 168

Patent

active

059358033

ABSTRACT:
Modulators of the immune system can be identified by determining the ability of candidate substances to affect the interaction of PKC-theta or a fragment thereof with its cognate. The interaction can be measured using binding of the cognate as an index, or can be measured using a physiological response.

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