Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-08-27
1978-03-07
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260250BN, 260250AH, 2602564C, 2602564N, 260288CF, 544212, 424250, C07D40106, C07D40114
Patent
active
040779580
ABSTRACT:
Compounds of the following formula ##STR1## wherein R.sup.1 and R.sup.2 are selected from hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, nitro, amino and cyano; Z is selected from ##STR2## R.sup.3 is selected from phenyl, phenyl-lower alkyl, substituted phenyl, and substituted phenyl-lower alkyl; R.sup.4 is selected from R.sup.3 and a 6-membered unsaturated substituted or unsubstituted heterocyclic ring selected from pyridine, diazine and triazine; and A is a straight or branched chain alkylene of 2 to 8 carbons are disclosed. These compounds exhibit antidepressant activity.
REFERENCES:
patent: 3935227 (1976-01-01), Wade et al.
patent: 3940397 (1976-02-01), Wade et al.
patent: 3940398 (1976-02-01), Wade et al.
patent: 4007191 (1977-02-01), Wade
Vogt Berthold Richard
Wade Peter C.
Daus Donald G.
Davis Stephen B.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Smith Merle J.
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