2-Saccharinylmethyl heterocyclic carboxylates useful as proteoly

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548210, 549 59, 514444, 514210, 514321, 5142338, 514253, 544135, 544368, 546198, A61K 31425, C07D24504

Patent

active

058563490

ABSTRACT:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.

REFERENCES:
patent: 5376653 (1994-12-01), Dunlap et al.
patent: 5488062 (1996-01-01), Dunlap et al.
patent: 5578623 (1996-11-01), Dunlap et al.

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